Multidisciplinary strategies in guided tissue regeneration: dentistry, biology, and bioengineering

Authors

  • Dr. Pablo Yael Carrazco Ávila Facultad de Odontología, Universidad Autónoma de Sinaloa, Josefa Ortiz de Domínguez s/n y Avenida de las Américas, Culiacán, Sinaloa, México. Author https://orcid.org/0000-0001-8638-6001
  • Mc. Teresa Anais Sauceda Vea Facultad de Odontología, Universidad Autónoma de Sinaloa, Josefa Ortiz de Domínguez s/n y Avenida de las Américas, Culiacán, Sinaloa, México. Author https://orcid.org/0009-0006-1361-1355
  • Dr. Jesús Eduardo Soto Sainz Facultad de Odontología, Universidad Autónoma de Sinaloa, Josefa Ortiz de Domínguez s/n y Avenida de las Américas, Culiacán, Sinaloa, México. Author https://orcid.org/0000-0002-3812-1727
  • Dr. Hipólito Castillo Ureta Posgrado en Ciencias Biológicas, Facultad de Biología, Universidad Autónoma de Sinaloa, Avenida de las Américas y Boulevard Universitarios S/N, Culiacán, Sinaloa 80013, México Author https://orcid.org/0000-0002-8361-9735
  • Dr. Jorge Armando López Gutiérrez Facultad de Odontología, Universidad Autónoma de Sinaloa, Josefa Ortiz de Domínguez s/n y Avenida de las Américas, Culiacán, Sinaloa, México. Author https://orcid.org/0000-0001-8137-0780

Keywords:

Guided tissue regeneration, Periodontics, Biomaterials, Membranes, Guided bone regeneration

Abstract

Objective: To synthesize the scientific advancements of the last decade in guided tissue regeneration (GTR) and guided bone regeneration (GBR), analyzing the evolution of membranes, biomolecules, platelet concentrates, nanomaterials, and biofabricated scaffolds from a translational research perspective. Data collection method: A narrative review of the literature published between 2016 and 2025 was conducted using MEDLINE (via PubMed) and Scopus databases. The search employed controlled terms and technical descriptors related to periodontics and biomaterials, prioritizing systematic reviews, consensus documents, and high-impact experimental studies. Development: The findings confirm that resorbable collagen membranes remain the gold standard due to their biocompatibility, while e-PTFE membranes are reserved for critical space maintenance. The use of adjuvants, such as Enamel Matrix Derivative (EMD) and Platelet-Rich Fibrin (PRF), enhances clinical attachment gain and bone fill. Furthermore, the integration of nanomaterials (bioactive glasses and nano-hydroxyapatite) and 3D printing has enabled the development of smart scaffolds that modulate the immune response and provide targeted pro-regenerative ionic release. Conclusions: The success of modern GTR/GBR demands interdisciplinary planning and a rational selection of active biomaterials. Although biofabrication and nanotechnology offer promising personalized solutions, their definitive clinical integration requires robust randomized clinical trials, standardization of protocols, and cost-effectiveness analyses to ensure predictability and safety in routine dental practice.

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Author Biography

  • Dr. Pablo Yael Carrazco Ávila, Facultad de Odontología, Universidad Autónoma de Sinaloa, Josefa Ortiz de Domínguez s/n y Avenida de las Américas, Culiacán, Sinaloa, México.

    Bachelor of Dental Surgery from the Autonomous University of Sinaloa, Mexico (2008–2013).
    Private Master's Degree in Oral Surgery and Implantology from the University of Granada, Spain (2014–2017).
    Official Master's Degree in Dental Sciences from the University of Granada, Spain (2017–2018).
    PhD in Clinical Medicine and Public Health from the University of Granada, Spain (2018–2024).

    My academic journey has been rooted in scientific research, with a particular focus on dental implant coatings for targeted drug delivery. Throughout my training, I have developed a strong theoretical and practical foundation that has enabled me to contribute to the advancement of knowledge in my field. I have also collaborated with multidisciplinary teams, employing advanced methodologies for the analysis, design, and evaluation of innovative materials. Among the tools I frequently use are ultraviolet-visible (UV-Vis) spectrophotometry, dynamic light scattering (DLS), and bacterial analysis techniques, which allow for process optimization and the achievement of precise and reproducible results.

    Additionally, I consider critical thinking and effective scientific communication to be essential skills, which I have strengthened through the writing of my doctoral thesis, scientific articles, and conference presentations. My goal is to continue generating impactful knowledge by applying innovative approaches and promoting technology transfer to improve quality of life and foster sustainable development.

    On a personal level, I am deeply committed to excellence, ethics, and lifelong learning. I enjoy teamwork, solving complex problems, and exploring new frontiers of knowledge. I firmly believe in the importance of interdisciplinarity and the need to adapt science to the demands of contemporary society and the ever-evolving technological landscape.

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Published

2026-05-19

Issue

No. 3 (2026): Núm. 3 (2026): REVOUAS Revista Odontológica UAS

Section

Revisiones Bibliográficas

How to Cite

Multidisciplinary strategies in guided tissue regeneration: dentistry, biology, and bioengineering. (2026). REVOUAS Revista Odontológica UAS, 1(3). https://revistas.uas.edu.mx/index.php/REVOUAS/article/view/1680