Anti-PROX1

Authors

Keywords:

Retina, Regeneration, Müller glial cells, Anti-PROX1 therapy, Vision

Abstract

The text discusses a scientific breakthrough developed by KAIST researchers in the field of retinal regeneration. It explains that millions of people suffer from retinal diseases that can lead to vision loss, and that there is currently no effective therapy to restore sight once it has been lost. The research suggests that, unlike fish, mammals cannot naturally regenerate the retina because the protein Prox1 accumulates in Müller glial cells and blocks regeneration. By inhibiting this protein through Anti-PROX1 therapy, these cells could be reprogrammed to produce new retinal cells, including photoreceptors and retinal ganglion cells, which are affected in diseases such as retinitis pigmentosa and glaucoma.

The described artwork represents this advance through a pair of eyes looking at a screen displaying the message “Anti-PROX1,” with a blue-toned fish in the background symbolizing natural retinal regeneration. Finally, the text reflects on the everyday impact of visual problems and presents the possibility of recovering sight without surgery or glasses as a shared hope for millions of people.

Downloads

Download data is not yet available.

Author Biography

  • Dra. Ruth Mora Rochín, Universidad Autónoma de Sinaloa.

    BIOGRAPHY

    RUTH MORA ROCHIN

    She was a student in the Technical Painting program at the Autonomous University of Sinaloa from 1995 to 1999. in 1999, she participated in an exchange program at the Polytechnic University of Valencia. She earned her Bachelor’s degree in Visual Arts from the University of Guadalajara from 1999 to 2003. In 2004, she joined the School of Plastic Arts at the Autonomous University of Sinaloa, where she currently works as an educator and ventures into the art world, participating in numerous art exhibitions. She achieved first place in the XXII Sinaloa Plastic Arts Salon. Additionally, her paintings have been exhibited internationally in countries such as Colombia and France.

    She served as the Coordinator of Leveling in Plastic Arts (2009-2010) for the Academic Unit of Plastic Arts. She has actively contributed to enhancing the curriculum of the subjects she teaches, attending numerous training courses. She pursued a master’s in education, Teaching, and Pedagogy, as well as a Doctorate in Education Sciences, at Santander University.

    In 2022, she joined the School of Design and Visual Arts at the Autonomous University of Sinaloa as an Administrative Secretary. She played a crucial role as a coordinator in the curricular reform of the study plans for the Bachelor’s in Design, Arts, and Multimedia, Bachelor’s in visual arts, and Bachelor’s in Photography and Video Production in the classroom-based modality. She also collaborated in the curricular reissue for the Bachelor’s in Photography and Video Production, complementary to the Higher Technical Professional Level in a mixed modality. Dr. Mora has actively participated in numerous workshops, seminars, forums as a speaker, and diploma programs to support her ongoing professional development in education.

References

Lee, E. J., Kim, M., Park, S., et al. (2025). Restauración del potencial regenerativo retiniano de la glía de Müller mediante la interrupción de la transferencia intercelular de Prox1. Nature Communications, 16 (1) 2928. https://doi.org/10.1038/s41467-025-58290-8

Meza Capcha, E. (2025, abril 4). Primer fármaco capaz de restaurar la visión mediante regeneración de células retinales. Infobae. https://www.infobae.com/peru/2025/04/04/primer-farmaco-capaz-de-restaurar-la-vision-mediante-regeneracion-de-celulas-retinales/#:~:text=C%C3%B3mo%20el%20f%C3%A1rmaco%20desarrollado%20por,enfermedades%20degenerativas%20de%20la%20retina

Portada: Anti-PROX1

Downloads

Published

2026-06-30

Issue

No. 7 (2026): SIBIUAS Revista de la Dirección General de Bibliotecas

Section

Artistic creations

Categories

License

Copyright (c) 2026 SIBIUAS Revista de la Dirección General de Bibliotecas

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

How to Cite

Mora Rochín, R. (2026). Anti-PROX1. SIBIUAS Revista De La Dirección General De Bibliotecas, 7, 10-13. https://revistas.uas.edu.mx/index.php/SIBIUAS/article/view/1343